6 Postdoctoral Positions at University of Saint Louis, USA


(1) Post Doctoral Fellow, Department of Pediatrics, Division of Medical Genetics

The candidate will join a dynamic, interdisciplinary team that uses cell biology, protein engineering, biochemistry, human immunology and molecular biology techniques to understand lysosomal dysfunction in rare genetic disorders. The successful candidate must be highly motivated with extensive experience within one or more of the following areas: single cell sequencing, cell culture, pharmacokinetics, pharmacodynamics, organelle, and cell/molecular biology, while experience with advanced imaging techniques is advantageous. We are particularly interested in candidates with experience in lysosomal biology.  The candidate is expected to conduct independent lab work and have a strong record of scientific productivity.   He or she should be able to think critically about complex problems and contribute to a team-working environment to advance research projects.

The Montaño laboratory is collaborative and supports diversity. The candidate will be responsible for working with other researchers, graduate, and undergraduate students in the lab and participate in maintaining a strong lab culture within the research group.  

The job requirements include a Ph.D. in biochemistry, cell biology, molecular biology or other relevant scientific field and from zero to four (0-4) years of post-doctoral experience.

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(2) Postdoctoral Fellow – Dr. Jianguo Liu’s Lab

70% of breast cancers are estrogen receptor-positive and treated successfully with endocrine therapy. However, 40% of patients relapse and die from metastases that are refractory or resist endocrine therapy. This position will investigate the molecular mechanisms of endocrine resistance and the potential of a new adjuvant therapy to restore the responsiveness of endocrine-resistant breast cancers to endocrine therapy.

One postdoctoral position is available immediately for junior scientists (Ph.D., D.V.M. or M.D.) with a strong background in molecular biology. Previous experience in conducting cell biology research and working with small animal is preferred.

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(3) Postdoctoral Fellow-Pharmacology and Physiology

NIH-funded postdoctoral positions are available for highly motivated postdoctoral fellows to join the laboratory of Dr. Aubin Moutal, in the Department of Pharmacology and Physiology at St Louis university to study novel proteins involved in chronic pain in the context of autoimmunity. Our work focuses on first identifying determinants of the transition from acute to chronic pain by reverse translating clinical findings to then perform a complete mechanistic characterization of how these new factors influence chronic vs physiological pain. The PI has a strong record of high impact papers with multiple recent publications in Science Translational Medicine, Pain, and PNAS. Through the active external collaborations with the New York University (Dr. Rajesh Khanna), the University of Arizona (Dr. Frank Porreca) and with the Institut neuromyogene (Dr. Jérôme Honnorat) in France, the candidate will also grow an interest in ion channel regulation, central mechanisms of pain and paraneoplastic syndromes, respectively.

Major techniques include immunohistochemistry, protein-protein interactions and protein biochemistry are employed to support findings from our behavioral and electrophysiological experiments. Applicants should have a strong background in animal surgeries and behaviors or electrophysiology or molecular biology, IF, IHC, Western analysis, and enzyme assays. Successful applicants will be highly motivated individuals with good communication skills, will have a proven publication record, and the ability to work independently. The applicants must currently have a Ph.D. in Biochemistry, Neuroscience or any related field. The appointment will be for 2 years with renewal up to 5 years and a competitive salary following NIH guidelines. Email a single PDF containing a CV, 1-2 pages summary of past research accomplishments, and contact information for three references to: aubin.moutal@health.slu.edu. All questions are welcome!

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(4) Postdoctoral Fellow-Pharmacology and Physiology

NIH-funded postdoctoral positions are available for highly motivated postdoctoral fellows to join the laboratory of Dr. Aubin Moutal, in the Department of Pharmacology and Physiology at St Louis university to study novel proteins involved in chronic pain in the context of autoimmunity. Our work focuses on first identifying determinants of the transition from acute to chronic pain by reverse translating clinical findings to then perform a complete mechanistic characterization of how these new factors influence chronic vs physiological pain. The PI has a strong record of high impact papers with multiple recent publications in Science Translational Medicine, Pain, and PNAS. Through the active external collaborations with the New York University (Dr. Rajesh Khanna), the University of Arizona (Dr. Frank Porreca) and with the Institut neuromyogene in France the candidate will also grow an interest in ion channel regulation, central mechanisms of pain and paraneoplastic syndromes, respectively.

Major techniques include immunohistochemistry, protein-protein interactions and protein biochemistry are employed to support findings from our behavioral and electrophysiological experiments. Applicants should have a strong background in molecular biology, IF, IHC, Western analysis, and enzyme assays; experience with phosphorylation, ubiquitination, and/or a mouse colony are pluses. Successful applicants will be highly motivated individuals with good communication skills, will have a proven publication record, and the ability to work independently. The applicants must currently have a Ph.D. in Biochemistry, Neuroscience or a related field. The appointment will be for 2 years with renewal up to 5 years and a competitive salary following NIH guidelines. Email a single PDF containing a CV, 1-2 pages summary of past research accomplishments, and contact information for three references to: aubinmoutal@gmail.com. All questions are welcome!

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(5) Post-Doctoral Fellow-Dr. Liu’s Lab

Saint Louis University, dedicated to student learning, research, health care, and service, is seeking applicants for a Postdoctoral Fellow in Dr. Jianguo Liu’s lab in the Departments of Internal Medicine and Molecular Microbiology and Immunology.

Tuberculosis (TB) remains a leading health problem worldwide. The lack of highly effective preventive vaccine, the emergence of drug-resistant strains, and an epidemic in HIV patients make TB a worsening threat. Host-directed therapy (HDT) is a promising approach for treating drug-resistant TB. This NIH-funded position is to investigate the host protective immune mechanisms and develop new HDT against Mycobacterium tuberculosis infection. 

Postdoctoral position is available immediately for researchers (Ph.D., D.V.M. or M.D.) with strong background in molecular biology and immunology. Previous experience in TB research is desired. 

This position is a full-time appointment with all benefits provided by SLU. Salary is dependent on qualifications and experience.

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(6) Post-Doctoral Fellow

Our NIH-funded laboratory is seeking an enthusiastic postdoctoral fellow to study the immunological response and pathogenesis of viral infections. Laboratory studies are focused on the understanding of the antigen specific B cell response to infection and vaccination and how this B cell response is reflected in the polyclonal antibody response. Our laboratory uses in vitro and in vivo approaches to understand infection and disease.  Techniques include cloning and molecular biology, biochemistry, cell/tissue culture, flow cytometry, transcriptomics, and mouse models of infection. Experience in one or more of these techniques and areas is strongly preferred. You will be provided with the mentorship and resources to be successful.

Primary Duties & Responsibilities:

Designs and conducts biomedical research experiments, including standard laboratory and molecular biology techniques, work with pathogenic viruses, and animal models of viral infection.

Independently evaluates own research findings and communicates these to the laboratory team, PI, and collaborators.

Prepares and delivers oral research presentations.

Prepares and submits research manuscripts to appropriate biomedical journals.

Provides guidance to graduate students and other junior trainees regarding their experiments and data interpretation.

Maintains conformity with ethical standards in research, including rules governing human subjects research and animal care and use.

Maintains compliance with good laboratory practice, including the maintenance of adequate research records.

Adheres to all applicable University policies, procedures and regulations.

Required Qualifications: Ph.D., M.D. or an equivalent terminal or doctoral degree.

Preferred Qualifications:

Demonstrated proven success working with cross functional groups

Experience in technical skills such as immunoassay, ELISA, viral propagation, virus culture and other antibody-based techniques

Results-oriented with proven track record of success in independently executing multiple projects simultaneously within a team environment.

Ability to manager projects, coordinate activities and present project

Excellent organizational, communication and interpersonal skills.

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